Medical Advice

Azelaic Acid vs Salicylic Acid: Which Acid is Best?

Azelaic Acid vs Salicylic Acid

Blemish and acne are common skin problems that occur in people in our everyday lives. Several ingredients are available to treat these problems in the medical industry. These ingredients include salicylic acid and azelaic acid. Now, we provide brief information on these and the difference between Azelaic Acid vs Salicylic Acid with their properties and benefits.

Overview of Azelaic Acid with its physical properties and benefits

Azelaic acid is an organic compound found in wheat, rye, and barley. It is used for the treatment of acne in individuals. Another name for azelaic acid is nonanedioic acid.

It includes several physical properties. These are as follows:

  • Its molecular mass is 188.223 g/mol.
  • Its density is 1.443 g/ml.
  • Its melting point is 109 degrees Celsius and its boiling point is 286 degree Celsius.
  • The refractive index of azelaic acid is 1.4303.
  • Azelaic acid is soluble in water.

Overview of Salicylic Acid

Salicylic acid is a beta-hydroxy acid (BHA) that treats acne and other skin problems by removing dead skin cells in people. It also treats redness, which is caused by hyperpigmentation, rosacea, and melasma.

The properties of salicylic acid are as follows:

  • Its molar mass is 138.121 g/mol.
  • The density of salicylic acid is 1.44 g/ml.
  • Its boiling point is 211 degrees Celsius and its melting point is 158.6 degrees Celsius.
  • It is soluble in oil.

Comparison Between Azelaic Acid and Salicylic Acid

Below are several comparisons of azelaic acid and salicylic acid:

Brand names

Azelaic Acid

The brand names of Azelaic acid are Finacea, Finacea Plus, and Azelex.

Salicylic Acid

Salicylic acid has various brand names. These names include Duoforte 27, Compound W Plus, Acnex, Clear Away Wart Removal System, Compound W One-step Wart Remover, Acnomel Acne Mask, Dr. Scholls Cushlin Ultra Slim Callus Removers, Dr. Scholls Cushlin Ultra Slim Corn Removers etc.


Azelaic Acid

The dosages of Azelaic acid are cream, gel, and foam. These dosages are available for the treatment of skin problems in adults and children.

Salicylic Acid

Soap, pad, gel, shampoo, bandage, liquid, spray, lotion, foam, spray, etc. are some dosages of salicylic acid available for the treatment of skin problems.


Azelaic Acid

The function of Azelaic acid is to clean out the pores that allow the skin to be free from bacteria while treating acne in the body. It is used for skin-lightening, which protects the body from cell discoloration.

Salicylic Acid

The function of Salicylic acid is to protect skin from dead skin cells such as pimples, blackheads, whiteheads, etc.

Side effects

Azelaic Acid

The side effects of Azelaic acid are as follows:

  • Eye Pain
  • Itching, dryness, or redness on the skin
  • Burning of the skin
  • Joint pain
  • Irritation
  • Breathing problem
  • Swelling on various body parts such as the tongue, lips, legs, throat, hands, face, eyelids, or sex organs.
  • Chest tightness
  • Irritation
  • Skin rashes
  • Fever

Salicylic Acid

There are different side effects of Salicylic Acid. These include the following:

  • Fainting
  • Stomach pain
  • Headache
  • Skin irritation
  • Diarrhea
  • Dizziness
  • Vomiting and nausea
  • Fast breathing
  • Throat tightness
  • Dryness, swelling, or redness of the skin


Azelaic acid

The common uses of Azelaic acid are as follows:

  • It is used in the polymer industries.
  • It is used to prevent acne and other skin problems in the medical industry.
  • Used also in the synthesis of protein.

Salicylic acid

The common uses of Salicylic acid are as follows:

  • Used to reduce muscle and joint pain in people.
  • It is used to produce medicinal drugs like aspirin.
  • It is used to prevent mouth ulcer problems in people.
  • It is useful for skin care production.
  • It is useful to treat wrath, acne, and dandruff in people.


This blog explains the differences between azelaic acid and salicylic acid. Both these acids are useful for the treatment of acne and other disorders in people. Both of them use different dosages for the treatment.

These acids also contain many side effects such as redness, swelling, vomiting, nausea, etc. You must consult with a doctor if you are suffering from these problems.

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